What is Visnadina?

Approaching the very wide world of cosmetics is not at all easy. For every need we are faced with an infinite range of brands and products. Everyone –obviously– They assure us that they are the perfect answer to our needs.

The most instinctive reaction is to give in to the flattery of the most broadcast advertising. Or, when in doubt, we choose the cheapest product, "which are all the same!". At best, we accept the advice of a friend (or friend) who had a great time.

But will it be good for us too?

The truth is that the best solution is to learn to recognize self the functionality and quality of the product we just took from the shelf.

I know, you're going to be protesting, "You can't have to get a degree to choose the next cream!" But it's nothing that difficult! With the pages of this blog, FGM04 wants to guide you through thand thebels that you find on the packaging of each product. Above all, you can decide by yourself Which product is worth your money!

The first step is certainly to learn to read thand thebel on the back of the package – theINCH (International Nomenclature of Cosmetic Ingredients).

Done? Fine! So are we autonomous? Not yet... Would you invite Mr. Vanillyl Butyl Ether to dinner? I guess you'd like to know who it is first. Here we get to the heart of the matter, because we have to find out what the substances that make up a cosmetic product are and how they act.

Visnadina, an ancient natural use.

Today we are dedicated to a plant substance of ancient use: the Visnadina. Where does it come from and what are its properties? Answering we will understand why FGM04 has selected it as an active ingredient cardinal for VISNA FORTE GEL, its new anti-cellulite line.

The molecule that we put under the magnifying glass in this article – Visnadine – is a phenolic compound. thet's see what that means.
Phenolic compounds are substances produced naturally from plants for an infinite number of purposes. They range from communication between one individual and another to defense against potentially harmful organisms. Without considering the attraction of those, instead, useful to the plant itself (such as pollinating insects).

All phenolic compounds, including Visnadine, belong to an important class of plant molecules: that of Secondary metabolites. These are all those substances that the plant produces out of necessity that go beyond those Primary, that is: growth and development.

Translating, secondary metabolites do not serve the functioning of all plants, but have been developed distinctly by the various species to allow adaptation to specific environmental conditions. So what? So this explains why it is not enough to pick the grass in the garden of the house to get the Visnadina!

Only a few species of plants belonging to the Apiacee family produce our molecule. The best known and used is the visnaga. Have you heard of it before? thet's take a closer look.

Ammi Visnaga

The visnaga is an annual plant that grows mainly in the Mediterranean area. It is characterized by the wide and delicate umbrella inflorescence composed of numerous white flowers. His Scientific name, in Thetin, is Ammi Visnaga, but is also known as khella and Visnaga daucoides.

the Medicinal properties Of this plant are known to man since the time of the pyramids. The Egyptians used it to produce a decoction effective against theasthma e i kidney stones. It also seems that they already knew its beneficial qualities for the treatment of psoriasis. So no... It is not exactly a discovery of contemporary science...

It does not mean, however, that we have limited ourselves to interpreting hieroglyphs!
Since the beginning of thand thest century the visnaga has been the interest of numerous studies in the medical and cosmetological fields. They are the fruits, in particular, to have proved to be rich in beneficial substances for humans. Among the most important – in addition to our Visnadinanaturally – we find the kellina and the visnagina, mainly responsible for the effects diuretics And spasmolitici of Vissonaga tea.

In short, the visnaga is a plant rich in resources! But why do we care own Visnadina?

Medicinal properties

La Visnadina is known for its vasodilatory and angiogenic properties. In practice, it induces the dilation of blood vessels at peripheral and coronary level and stimulates the formation of new vessels, thus increasing the circulation. For these virtues, Visnadina has already been used to treat theangina pectoris. 
Someone might wonder: "But then if I get a heart attack I should get a decoction of herbs?

Better to clarify!

Angina is often associated with cardiac arrest because, in fact, it precedes it. In reality But angina is, more precisely, the pain in the chest and left arm that occurs when the heart is not sufficiently oxygenated. This condition is generally due to an occlusion of the coronary arteries, responsible for feeding and oxygenating the heart. If the occlusion is only partial, the ache Angina can also occur with recurrence without necessarily resulting in a heart attack.
More recently, aInteresting Possibility of use of our molecule. The stimulating action on blood supply can be exploited to help women suffering from Disorder ofsexual arousal.

You don't need to open another page! Let me explain right away.
Female sexual arousal, at the corporeal, involves the activation of genital tissues with increment blood supply and secretion of lubricating fluid from the vaginal walls.

When this aspect of sexual stimulation is compromise In a persistent or recurrent way we speak of female sexual arousal disorder, precisely. It follows the difficulty in initiating or ending sexual intercourse. The repercussions of the disorder in the psychological sphere are easily understood.

You will have already understood where we are going: the application of Visnadina at the vulvar level has proven to be a Powerful tumescence activator – or swelling – and lubrication of the genitals.

No, you cannot use VISNA FORTE GEL DONNA as a lubricant!
For use on intimate parts you need a specially designed product.
In addition to vasodilatory action, laboratory experiments suggest that Visnadina is capable of an important effect anti-inflammatory.

Even stopping here we could safely insert this product of visnaga in the arsenal of plant molecules useful to man. But it's not over yet!

The cosmetic utility against cellulite

Never heard of cellulite?
"Is there anyone who doesn't know what it is?" You will answer me rightly! In fact, cellulite affects about 9 out of 10 post-pubertal women5. Not that men are immune, but it is true that male cellulite occurs much more rarely.

Although it is not a pathological condition, the resulting skin blemish – the famous 'orange peel' – turns out to be a problem and a reason for discomfort for most women.

Unfortunately, the cause of cellulite are still unclear. In addition, it is a complex phenomenon which involves numerous tissue aspects of the skin. Do we surrender to difficulty? No!

One of the main constituents of cellulite are fat deposits, or fat, located under the skin of the affected areas. Generally these are the thighs and buttocks: precisely the parts of the body that in women are more resistant the elimination of fats, even with sports.

Visnadine stimulates adipocytes – the cells used for the accumulation of fat – to to increase their lipolytic activity 6,7. That is?

In other words, our molecule does not dissolve magically fat, but communicates to the cells of break Fat molecules – I triglycerides – which are then released into circulation. Lipolytic action arranged with that of stimulation on blood microcirculation, make Visnadina a valid natural tool to counteract cellulite.

This is why FGM04 has decided to include it as an active ingredient in its cosmetics dedicated to physiologically rebalancing the tissue structure of the skin: VISNA FORTE GEL DONNA And VISNA FORTE GEL MAN.

Concluding

In the previous article, we had got acquainted with the Phosphatidylcholine. Today we have added a second molecule to our inventory of substances that we can recognize immediately when we read theINCH of a product.

We learned that the Visnadina:

  • is a natural molecule produced by various plants belonging to the Apiacee family, among which the visnaga stands out;
  • it has a vasodilatory action at the level of peripheral and coronary vessels and therefore favors tissue circulation;
  • It promotes the lipolytic activity of adipocytes and blood microcirculation with positive effects against cellulite.

And we also discovered the ancient medicinal uses of Ammi Visnaga, today confirmed and explained by modern science.

Now you understand why the Visnadina is important for us at FGM04. From this molecule VISNA FORTE GEL It draws its main strength, which makes it so effective for revitalizing and rejuvenating the skin and fighting cellulite.

Was it difficult? Maybe a little, all right! But I am sure that as soon as you read the name of this molecule on the packaging of a product you will be rewarded by the satisfaction to know for yourself the cosmetic effects.

In the next article we will get acquainted with a widely used active ingredient, also in our cosmetic line: the Vanillyl Butyl Ether. Just what we didn't know whether to invite to dinner!

References

1. Duarte, Juan, et al. “Effects of visnadine on rat isolated vascular smooth muscles.” Medical plant 63.03 (1997): 233-236.
2. Bassino, Eleonora, et al. “Effects of flavonoid derivatives on human microvascular endothelial cells.” Natural product research 30.24 (2016): 2831-2834.
3. Caruso, Salvatore, et al. “Randomized crossover study investigating daily versus on-demand vulvar Visnadine spray in women affected by female sexual arousal disorder.” Gynecological Endocrinology (2017): 1-5.
4. Menghini, Luigi, et al. “Antiinflammatory activity of coumarins from Ligusticum lucidum Mill. subsp. cuneifolium (casting.) Tammaro (Apiaceae)." Phytotherapy research 24.11 (2010): 1697-1699.
5. Janda, K., and A. Tomikowska. “Cellulite-causes, prevention, treatment.” Annales Academiae Medicae Stetinensis. Vol. 60. No. 1. 2014.
6. Thastrup, Ole, Bjarne Fjalland, and John Lemmich. “Coronary Vasodilatory, Spasmolytic and cAMP‐Phosphodiesterase Inhibitory Properties of Dihydropyranocoumarins and Dihydrofuranocoumarins.” Basic & Clinical Pharmacology & Toxicology 52.4 (1983): 246-253.
7. Duncan, Robin E., et al. “Regulation of lipolysis in adipocytes.” Annu. Rev. Nutr. 27 (2007): 79-101.

Author: Roberto – molecular biologist